‍About This Service‍

At Wholesome Clinic, we offer Spravato® — a cutting-edge, FDA-approved treatment designed for individuals living with treatment-resistant depression and major depressive disorder with suicidal thoughts.

If you’ve tried two or more antidepressants without relief, Spravato offers new hope. This fast-acting therapy is administered in a safe, supportive environment by our clinical team with expertise in advanced psychiatric care.

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What Is Spravato?‍

Spravato is the brand name for esketamine, a nasal spray form of ketamine that works differently from traditional antidepressants. Rather than targeting serotonin or dopamine, Spravato affects the glutamate system, a key neurotransmitter network involved in learning, memory, and mood.

This unique mechanism helps rapidly restore brain connections disrupted by depression — leading to faster, more profound improvements in mood and functioning.‍

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How Spravato Works‍

Unlike oral medications that take weeks to work, Spravato delivers relief within hours to days for many patients. It helps rewire brain circuits affected by chronic depression, offering both symptom relief and improved resilience.

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What to Expect‍

1. Comprehensive Evaluation
Your journey begins with a thorough mental health assessment. We’ll review your medical and treatment history, assess for eligibility, and develop a personalized care plan.

2. In-Clinic Treatment Sessions
Spravato is self-administered as a nasal spray, but only under direct medical supervision. The initial course includes:

• Two sessions per week for four weeks
  
• Followed by maintenance sessions once symptoms begin to improve
  

3. Post-Dose Monitoring
After each treatment, you’ll stay in a comfortable recovery area for about two hours for monitoring. Side effects such as dizziness, disconnection, or drowsiness are typically mild and short-lived.

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Why Patients Choose Spravato‍

• Fast relief from depressive symptoms — May provide relief fast, often within days
  
• Ideal for treatment-resistant depression when other medications have failed
  
• Can reduce suicidal thoughts, improving safety and emotional stability
  
• No IVs required — a nasal spray administered in a calming, clinical setting
  

Improves quality of life, helping you reconnect with your daily routine, relationships, and goals.

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Is Spravato Right for You?‍

You may be a candidate for Spravato if:
✔ You’ve tried two or more antidepressants without improvement
✔ You experience persistent or severe depression
✔ You’ve had thoughts of self-harm or suicidal ideation despite treatment

We’re here to guide you through every step — with compassion, privacy, and expertise.

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Where Treatment Is Offered‍

In-Person: Administered at our Plano, Texas clinic

• In-Person: Administered at our Plano, Texas clinic
  
• Coming Soon: On-site Ketamine Infusion Therapy for expanded support options.